2-ETHYNYLPYRIDINE synthesis
- Product Name:2-ETHYNYLPYRIDINE
- CAS Number:1945-84-2
- Molecular formula:C7H5N
- Molecular Weight:103.12
86521-05-3
1945-84-2
The general procedure for the synthesis of 2-ethynylpyridine from 2-pyridynyltrimethylsilane was as follows: 2-((trimethylmethylsilyl)ethynyl)pyridine (175 mg, 1.0 mmol) was dissolved in a mixed solvent of methanol/dichloromethane (2 mL/1 mL). The reaction system was cooled to 0 °C and potassium hydroxide (112 mg, 2.0 mmol) was subsequently added. After stirring the reaction mixture for 0.5 h at 0 °C, the reaction was quenched with deionized water. The reaction mixture was extracted with dichloromethane (2 x 3 mL) and the organic phases were combined. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the target product 2-ethynylpyridine (80 mg, 80% yield).
86521-05-3
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1945-84-2
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1121-60-4
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90965-06-3
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1945-84-2
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29767-97-3
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1945-84-2
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![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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1945-84-2
230 suppliers
$12.00/1g