2-FLUORO-4-(2-HYDROXYPROPAN-2-YL)BENZOIC ACID synthesis
- Product Name:2-FLUORO-4-(2-HYDROXYPROPAN-2-YL)BENZOIC ACID
- CAS Number:1418128-37-6
- Molecular formula:C10H11FO3
- Molecular Weight:198.19
350-28-7
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$8.00/1g
1418128-37-6
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$612.00/1g
Yield:-
Steps:
Multi-step reaction with 5 steps
1.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 24 h / Reflux
2.1: silver nitrate / water; ethanol / 1.33 h / 50 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C
3.2: 20 °C
4.1: aminosulfonic acid; sodium chlorite / water; acetonitrile / 1.5 h / 20 °C
5.1: tetrahydrofuran; diethyl ether / 5 h / 0 °C
References:
Angst, Daniela;Gessier, Fran?ois;Janser, Philipp;Vulpetti, Anna;W?lchli, Rudolf;Beerli, Christian;Littlewood-Evans, Amanda;Dawson, Janet;Nuesslein-Hildesheim, Barbara;Wieczorek, Grazyna;Gutmann, Sascha;Scheufler, Clemens;Hinniger, Alexandra;Zimmerlin, Alfred;Funhoff, Enrico G.;Pulz, Robert;Cenni, Bruno [Journal of Medicinal Chemistry,2020,vol. 63,# 10,p. 5102 - 5118]
777074-51-8
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1418128-37-6
21 suppliers
$612.00/1g
193290-80-1
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$110.00/1g
1418128-37-6
21 suppliers
$612.00/1g
74733-25-8
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$75.00/500mg
1418128-37-6
21 suppliers
$612.00/1g