ChemicalBook CAS DataBase List 2-HEXYLDECANOIC ACID

2-HEXYLDECANOIC ACID synthesis

9synthesis methods

Product Name:2-HEXYLDECANOIC ACID
CAS Number:25354-97-6
Molecular formula:C16H32O2
Molecular Weight:256.42

67-56-1 Synthesis

67-56-1
727 suppliers
$9.00/25ml

544-10-5 Synthesis

544-10-5
229 suppliers
$13.00/5g

111-11-5 Synthesis

111-11-5
333 suppliers
$15.68/25ML

25354-97-6
131 suppliers
$10.00/1g

Yield:25354-97-6 91.3%

Reaction Conditions:

Stage #1: methanol;1-Chlorohexane;methyl octanatewith sodium hydroxide at 20 - 60; for 6 h;Large scale;
Stage #2: with water;sodium hydroxide at 60; for 6 h;Large scale;

Steps:

1.S1-1.S3 Example 1:

A synthesis method of Guerbet acid includes the following steps:
S1, at 2030,Dissolve 1000g of methyl octoate and 303.34g of sodium hydroxide in 4000g of methanol and add it to the reactor.Then slowly add 1067.17g chloro-n-hexane,After the addition, the temperature was raised to 60°C and reacted for 6h;
S2. Dissolve 303.34g sodium hydroxide in 568.76g water and slowly add it to the reaction tank.Continue the reaction at 60°C for 6h, and distill off the solvent under reduced pressure;
S3, drop to room temperature,Add 1mol/L hydrochloric acid solution to neutralize the system pH=34,Allow to stand, separate, and the organic phase is dissolved in 1000mL petroleum ether,Add 2000mL water to wash twice, add 16.20g activated carbon to decolor,The low boiling point components were distilled off under reduced pressure at 80°C to obtain 1479.50g of colorless transparent liquid.It is 2-hexyldecanoic acid with a yield of 91.30% and a purity of >98%.

References:

CN111269083,2020,A Location in patent:Paragraph 0026-0030; 0041-0050

334-48-5 Synthesis