ChemicalBook CAS DataBase List 2-Methoxy-5-(trifluoromethyl)aniline

2-Methoxy-5-(trifluoromethyl)aniline synthesis

10synthesis methods

Product Name:2-Methoxy-5-(trifluoromethyl)aniline
CAS Number:349-65-5
Molecular formula:C8H8F3NO
Molecular Weight:191.15

394-25-2 Synthesis

394-25-2
145 suppliers
$6.00/5g

349-65-5
254 suppliers
$5.00/1g

Yield:349-65-5 99%

Reaction Conditions:

with hydrogen;palladium 10% on activated carbon in methanol at 20;

Steps:

51.1

Example 51Synthesis of 4-(8-methoxy-5- (trifluorornethyl) quinazolin-2-ylamino) phenyl)(moφholino)methanone (Compound 500) PP028218.0002Step 1. Preparation of 2-methoxy-5- (trifluoromethyl) anilineA mixture of 4-methoxy-3-nitrobezotrifluoride and 10% of 10% Pd / C in methanol was stirred under Hfe atmosphere overnight at room temperature. The reaction mixture was filtered through celite, concentrated and dried under vacuum to provide product as an off white solid in 99%yield. ES/MS m/z 192.1 (MH⁺).

References:

WO2007/117607,2007,A2 Location in patent:Page/Page column 363-364

394-25-2 Synthesis

394-25-2
145 suppliers
$6.00/5g

7439-89-6
408 suppliers
$10.00/25g

349-65-5
254 suppliers
$5.00/1g

References

402-52-8
133 suppliers
$14.00/1g

349-65-5
254 suppliers
$5.00/1g

References

402-10-8 Synthesis

3-Bromo-4-methoxybenzotrifluoride2-Methoxy-5-trifluoromethyl bromobenzene

402-10-8
61 suppliers
$10.00/1g

349-65-5
254 suppliers
$5.00/1g

References

98-56-6 Synthesis

98-56-6
389 suppliers
$11.00/25g

349-65-5
254 suppliers
$5.00/1g

References

2-Methoxy-5-(trifluoromethyl)aniline Related Search:

Betaine Glycine 2-Aminobenzotrifluoride 2-Methyl-4-methoxybenzenamine N-Methylaniline N,N-Dimethylaniline Aniline 3-(Trifluoromethyl)benzaldehyde 2-(Trifluoromethoxy)aniline 2,3-DIAMINOTOLUENE