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2-methyl-2-(2-methylphenoxy)propanoic acid synthesis

8synthesis methods
-

Yield:53498-62-7 51%

Reaction Conditions:

with sodium hydroxide in water at 70; for 2 h;

References:

Shamovsky, Igor;De Graaf, Chris;Alderin, Lisa;Bengtsson, Malena;Bladh, H?kan;B?rjesson, Lena;Connolly, Stephen;Dyke, Hazel J.;Van Den Heuvel, Marco;Johansson, Henrik;Josefsson, Bo-G?ran;Kristoffersson, Anna;Linnanen, Tero;Lisius, Annea;M?nnikk?, Roope;Nordén, Bo;Price, Steve;Ripa, Lena;Rognan, Didier;Rosendahl, Alexander;Skrinjar, Marco;Urbahns, Klaus [Journal of Medicinal Chemistry,2009,vol. 52,# 23,p. 7706 - 7723] Location in patent:supporting information; experimental part

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