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o-Cresol structure
Chemical Name:
o-toluol;o-Kresol;O-CRESOL;2-Cresol;FEMA 3480;Orthocresol;ORTHO CRESO;ortho-cresol;o-Oxytoluene;o-CRESOL pure
Molecular Formula:
Formula Weight:
MOL File:

o-Cresol Properties

Melting point:
30-34 °C
Boiling point:
191 °C
1.048 g/mL at 25 °C
vapor density 
3.72 (vs air)
vapor pressure 
0.3 mm Hg ( 20 °C)
refractive index 
3480 | O-CRESOL
Flash point:
178 °F
storage temp. 
10.2(at 25℃)
Liquid or Low Melting Solid
white to brown
4.8 (20g/l, H2O, 20℃)
explosive limit
1.47%, 148°F
Water Solubility 
20 g/L (20 ºC)
JECFA Number
Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, bases.
CAS DataBase Reference
95-48-7(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2-methyl-(95-48-7)
EPA Substance Registry System
Phenol, 2-methyl-(95-48-7)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  T
Risk Statements  24/25-34-39/23/24/25-23/24/25
Safety Statements  36/37/39-45-36/37
RIDADR  UN 3455 6.1/PG 2
WGK Germany  1
RTECS  GO6300000
Autoignition Temperature 555 °C
HazardClass  6.1
PackingGroup  II
HS Code  29071200
Hazardous Substances Data 95-48-7(Hazardous Substances Data)
Toxicity LD50 orally in rats: 1.35 g/kg (Deichmann, Witherup)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

NFPA 704

Diamond Hazard Value Description
Flammability   2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

o-Cresol price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 36922 o-Cresol analytical standard 95-48-7 250mg $19.6 2018-11-13 Buy
Sigma-Aldrich 40250-U 2-Methylphenol solution certified reference material, 5000 μg/mL in methanol 95-48-7 u $44.6 2018-11-13 Buy
TCI Chemical C0402 o-Cresol >99.0%(GC) 95-48-7 25g $16 2018-11-22 Buy
TCI Chemical C0402 o-Cresol >99.0%(GC) 95-48-7 500g $40 2018-11-22 Buy
Alfa Aesar A12307 o-Cresol, 98+% 95-48-7 500g $42 2018-11-13 Buy

o-Cresol Chemical Properties,Uses,Production

Chemical Properties

colourless to light yellow liquid

Chemical Properties

Cresol is a mixture of the three isomeric cresols, o-, m-, and p-cresol. Cresols are slightly soluble in water. m-Isomer: Colorless or yellow liquid with characteristic odor.

Chemical Properties

o-Cresol has a musty, phenolic aftertaste.


Reported in Acacial farnesiana, ylang-ylang oil (probably as p-cresyl acetate), jasmine absolute, orange oil from leaves, the essence from flowers of Lilium candidum, anise seed oil, the essence of Artemisia santolinoflia, and some sea algae. Also reported found in asparagus, peppermint oil, cheddar cheese, provolone cheese, butter, milk, lean fish, boiled egg, smoked pork, rum, Scotch whiskey, red wine, white wine, coffee and mango.Reported found in cinnamon, coffee, Oriental tobacco, rum, sherry, tea, tomato and whiskey.


ChEBI: A cresol that is phenol substituted by a methyl group at position 2. It is a minor urinary metabolite of toluene.

Aroma threshold values

Aroma characteristics at 1.0%: phenolic, medicinal, sweet spicy, smoky with a methyl salicylate nuance.

Taste threshold values

Taste characteristics at 2.0 ppm: sweet medicinal, phenolic and tarlike.

General Description

Colorless or yellow to brown-yellow or pinkish colored liquid with a phenol-like odor. Toxic by ingestion and/or skin absorption. May have a flash point between 100 and 199°F. Causes burns to skin, eyes and mucous membranes. Insoluble in water.

Air & Water Reactions

Sensitive to light and air. Insoluble in water.

Reactivity Profile

o-Cresol is incompatible with oxidizing agents and bases. Mixing o-Cresol with chlorosulfonic acid, nitric acid and oleum in a closed contained caused the temperature and pressure to increase.


Questionable carcinogen.

Health Hazard

The chemical is rated as a very toxic compound with a probable oral lethal dose in humans of 50-500 mg/kg, or between 1 teaspoon and 1 ounce for a 70 kg (150 lb.) person. It is a strong dermal irritant and frequently causes dermatitis. Serious or fatal poisoning may result if large areas of skin are wet with cresol, o- and the substance is not removed immediately. Ingestion of even a small amount may cause paralysis and coma. It is corrosive to body tissues, with toxicity similar to phenol.

Fire Hazard

Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. o-Cresol may burn but does not ignite readily. Container may explode in heat of fire. Slight explosion and fire hazard in the form of vapor when exposed to heat or flame. When heated to decomposition, o-Cresol emits highly toxic fumes. Reacts violently with nitric acid, oleum, and chlorosulfonic acid. Hazardous polymerization may not occur.

Safety Profile

Poison by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by skin contact. A severe eye and skin irritant. Human mutation data reported. Questionable carcinogen with experimental neoplastigenic data. Flammable when exposed to heat, flame, or oxidants. To fight fire, water may be used to blanket fire; foam, fog, mist, dry chemical. See also other cresol entries and PHENOL.

Potential Exposure

Cresol is used as a disinfectant and fumigant; as an ore flotation agent, and as an intermediate in the manufacture of chemicals, dyes, plastics, and antioxidants. A mixture of isomers is generally used; the concentrations of the components are determined by the source of the cresol.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema Cresols 931 may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy


UN2076 Cresols, liquid, Hazard class: 6.1; Labels: 6.1-Poisonous materials, 8-Corrosive material. UN3455 Cresols, solid, Hazard class: 6.1; Labels: 6.1- Poisonous materials, 8-Corrosive material.

Purification Methods

It can be freed from m-and p-isomers by repeated fractional distillation, It crystallises from *benzene by addition of pet ether. It has been fractionallly crystallised by partial freezing of its melt. The 3,5-dinitrobenzoate (prepared with 3,5-dinitrobenzoyl chloride in dry pyridine, and recrystallised from EtOH or aqueous Me2CO) has m 138o. [Beilstein 6 IV 1940.]


Vapors may form explosive mixture with air. Incompatible with strong acids; oxidizers, alkalies, aliphatic amines; amides, chlorosulfonic acid; oleum. Decomposes on heating, producing strong acids and bases, causing fire and explosion hazard. Liquid attacks some plastics and rubber. Attacks many metals.

Waste Disposal

Wastewaters may be subjected to biological treatment. Concentrations may be further reduced by ozone treatment. High concentration wastes may be destroyed in special waste incinerators.

o-Cresol Preparation Products And Raw materials

Raw materials

Preparation Products

o-Cresol Suppliers

Global( 263)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19919 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21924 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Anhui Royal Chemical Co., Ltd.
+86-025-86736275 CHINA 488 55
career henan chemical co
+86-371-86658258 CHINA 20516 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20094 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4660 58
(323) 306-3136
(626) 453-0409 United States 8409 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 China 24991 65

View Lastest Price from o-Cresol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 o-Cresol
US $1.00 / kg 1g 99% 100KG career henan chemical co

o-Cresol Spectrum

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