ChemicalBook CAS DataBase List 2-PYRIDIN-2-YL-1H-INDOLE

2-PYRIDIN-2-YL-1H-INDOLE synthesis

10synthesis methods

Product Name:2-PYRIDIN-2-YL-1H-INDOLE
CAS Number:13228-40-5
Molecular formula:C13H10N2
Molecular Weight:194.23

1121-60-4
495 suppliers
$10.60/10gm:

95-53-4 Synthesis

95-53-4
426 suppliers
$10.00/1g

13228-40-5
80 suppliers
$53.00/100mg

Yield: 77.3%

Reaction Conditions:

with toluene-4-sulfonic acid in toluene for 5 h;Reflux;

Steps:

1 Synthesis Example 1. Synthesis of Compound A1
Pyridine-2-carbaldehyde (10 mmol) and o-methylaniline (1.1 eq) were mixed and dissolved in toluene, and a catalytic amount of p-toluenesulfonic acid was added thereto, and heated to reflux to separate water for 5 hours. The reaction was completed, and the reaction solution was concentrated and passed through a column layer. The fraction was isolated to give 1.5 g of Intermediate M1, yield 77.3%.

References:

Beijing Dingcai Technology Co., Ltd.;Gu'an Dingcai Technology Co., Ltd.;Xing Qifeng;Li Zhiyang;Liu Shuyao;Ren Xueyan CN109251195, 2019, A Location in patent:Paragraph 0062; 0063; 0065; 0066

7734-05-6 Synthesis