Ethyl (2Z,5S,6E)-5-{[tert-Butyl(dimethyl)silyl]oxy}-2,6-dimethyl-7-(2-methyl-1,3-thiazol-4-yl)hepta-2,6-dienoate synthesis
- Product Name:Ethyl (2Z,5S,6E)-5-{[tert-Butyl(dimethyl)silyl]oxy}-2,6-dimethyl-7-(2-methyl-1,3-thiazol-4-yl)hepta-2,6-dienoate
- CAS Number:218614-04-1
- Molecular formula:C21H35NO3SSi
- Molecular Weight:409.66
![ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE](/CAS/GIF/107905-52-2.gif)
107905-52-2
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$120.00/100mg
188730-08-7
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218614-04-1
13 suppliers
$85.00/250mg
Yield:218614-04-1 5.45 g
Reaction Conditions:
Stage #1: ethyl 2-[bis(2,2,2-trifluoroethyl)phosphono]propionatewith 18-crown-6 ether;potassium hexamethylsilazane in tetrahydrofuran; for 0.25 h;
Stage #2: (3S,4E)-3-{[tert-butyl(dimethyl)silyl]oxy}-4-methyl-5-(2-methyl-1,3-thiazol-4-yl)pent-4-en-1-al in tetrahydrofuran at -78; for 0.5 h;Further stages.;Wittig olefination;
References:
Mulzer, Johann;Mantoulidis, Andreas;Oehler, Elisabeth [Journal of Organic Chemistry,2000,vol. 65,# 22,p. 7456 - 7467]
188730-08-7
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218614-04-1
13 suppliers
$85.00/250mg
![(-)-(3S)-3-([TERT-BUTYL(DIMETHYL)SILYL]OXY)DIHYDROFURAN-2(3H)-ONE](/StructureFile/ChemBookStructure7/GIF/CB0321055.gif)
164264-14-6
17 suppliers
$115.00/500mg
218614-04-1
13 suppliers
$85.00/250mg
![(-)-(3S)-3-([TERT-BUTYL(DIMETHYL)SILYL]OXY)-5-HYDROXYPENTAN-2-ONE](/StructureFile/ChemBookStructure7/GIF/CB7377268.gif)
218615-21-5
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$70.00/500mg
218614-04-1
13 suppliers
$85.00/250mg
39238-07-8
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$13.43/250mgs:
218614-04-1
13 suppliers
$85.00/250mg