3-Quinolinecarboxylic acid, 6-bromo-8-fluoro-4-hydroxy-, ethyl ester synthesis
- Product Name:3-Quinolinecarboxylic acid, 6-bromo-8-fluoro-4-hydroxy-, ethyl ester
- CAS Number:228728-06-1
- Molecular formula:C12H9BrFNO3
- Molecular Weight:314.11
Yield:228728-06-1 88%
Reaction Conditions:
with diphenylether at 230; for 0.5 h;
References:
Knutson, Daniel E.;Kodali, Revathi;Divovi?, Branka;Treven, Marco;Stephen, Michael R.;Zahn, Nicolas M.;Dobri?i?, Vladimir;Huber, Alec T.;Meirelles, Matheus A.;Verma, Ranjit S.;Wimmer, Laurin;Witzigmann, Christopher;Arnold, Leggy A.;Chiou, Lih-Chu;Ernst, Margot;Mihovilovic, Marko D.;Savi?, Miroslav M.;Sieghart, Werner;Cook, James M. [Journal of Medicinal Chemistry,2018,vol. 61,# 6,p. 2422 - 2446] Location in patent:supporting information
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