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ChemicalBook CAS DataBase List (1R,2R)-Methyl 2-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate
267230-27-3

(1R,2R)-Methyl 2-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate synthesis

4synthesis methods
267230-26-2 Synthesis
Cyclohexanecarboxylic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1S,2R)-

267230-26-2
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Yield:267230-27-3 70%

Reaction Conditions:

with sodium methylate in methanol; for 5 h;Heating;Isomerization;

References:

Appella, Daniel H.;LePlae, Paul R.;Raguse, Tami L.;Gellman, Samuel H. [Journal of Organic Chemistry,2000,vol. 65,# 15,p. 4766 - 4769]