N2,N2-DIMETHYL-3-(TRIFLUOROMETHYL)PYRIDINE-2,5-DIAMINE synthesis
- Product Name:N2,N2-DIMETHYL-3-(TRIFLUOROMETHYL)PYRIDINE-2,5-DIAMINE
- CAS Number:288247-16-5
- Molecular formula:C8H10F3N3
- Molecular Weight:205.18
813425-49-9
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288247-16-5
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$320.00/250mg
Yield:288247-16-5 34%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol at 20; for 1 h;
Steps:
104.3 Step 3:
N,N-dimethyl-5-nitro-3-(trifluoromethyl)pyridin-2-amine (200 mg, 0.85 mmol) was dissolved in methanol. 10 % Pd / C (40 mg) was added to it. The resulting mixture was stirred at room temperature under hydrogen atmosphere for 1 h. The mixture was filtered through celite bed and the filtrate was concentrated under reduced pressure to afford the N2,N2-dimethyl-3-(trifluoromethyl)pyridine-2,5-diamine (60 mg, 34 %).
References:
WO2013/13817,2013,A1 Location in patent:Page/Page column 131
25391-60-0
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288247-16-5
11 suppliers
$320.00/250mg
99368-67-9
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288247-16-5
11 suppliers
$320.00/250mg