3-([1,1-BIPHENYL]-4-YL)PROPIOLIC ACID synthesis

8synthesis methods

Product Name:3-([1,1-BIPHENYL]-4-YL)PROPIOLIC ACID
CAS Number:32340-38-8
Molecular formula:C15H10O2
Molecular Weight:222.24

124-38-9
122 suppliers
$214.00/14L

29079-00-3 Synthesis

29079-00-3
127 suppliers
$9.00/250mg

32340-38-8
19 suppliers
inquiry

Yield:32340-38-8 96%

Reaction Conditions:

Stage #1: carbon dioxide;4-biphenylylacetylenewith Cs₂CO₃ in (methylsulfinyl)methane at 40; under 760.051 Torr; for 20 h;Inert atmosphere;Schlenk technique;
Stage #2: with hydrogenchloride in lithium hydroxide monohydrate;(methylsulfinyl)methane;

References:

Shi, Kai;Lu, Chengrong;Zhao, Bei [New Journal of Chemistry,2022,vol. 46,# 35,p. 16998 - 17003] Location in patent:supporting information

1591-31-7 Synthesis