3,3-DIHYDROXYBENZYL synthesis
- Product Name:3,3-DIHYDROXYBENZYL
- CAS Number:63192-57-4
- Molecular formula:C14H10O4
- Molecular Weight:242.23
63192-58-5
6 suppliers
inquiry
63192-57-4
13 suppliers
inquiry
Yield:63192-57-4 45%
Reaction Conditions:
with nitric acid in acetone at 50 - 70;
Steps:
Synthesis of hydroxy benzils (8-14)
General procedure: Hydroxy benzoins (100-400 mg) were dissolved in acetone (5 mL) and conc.HNO3 (2-3 mL) was added, and the reactions were stirred at 50-70 °C for 30-120 min [31]. The reactions were terminated after the TLC control. Acetone was evaporated, then water (30 mL) was added to the flask, extracted with ethyl acetate(3×30 mL) to give crude mixture then compounds 8-15 were purified with repeated VLC (Silica gel 230-400 mesh) usingthe increasing polarity of n-hexane, chloroform, ethyl acetate, and methanol solvent mixtures, and the fractions werechecked by TLC (Figure). The synthesis of compounds 8 [23], 9 [9], 11 [44], and 15 [commercial product] had beenmentioned in the literature.
References:
Yayli, Nurettin;Kili?, G?zde;Celik, Gonca;Kahriman, Nuran;Kanbolat, Seyda;Bozdeveci, Arif;Karaoglu, Sengül Alpay;Aliyazicioglu, Rezzan;Sellitepe, Hasan Erdin?;Dogan, Inci Selin;Aydin, Ali [Turkish Journal of Chemistry,2021,vol. 45,# 3,p. 788 - 804]
40101-17-5
64 suppliers
$32.03/1g
63192-57-4
13 suppliers
inquiry
626-02-8
303 suppliers
$9.00/5g
63192-57-4
13 suppliers
inquiry
388061-72-1
16 suppliers
$146.66/1g
63192-57-4
13 suppliers
inquiry
100-83-4
647 suppliers
$5.00/10g
63192-57-4
13 suppliers
inquiry