3-(3-furyl)-3-oxopropanenitrile synthesis
1synthesis methods
- Product Name:3-(3-furyl)-3-oxopropanenitrile
- CAS Number:96220-13-2
- Molecular formula:C7H5NO2
- Molecular Weight:135.12
Yield:96220-13-2 39%
Reaction Conditions:
Stage #1: acetonitrilewith n-butyllithium in tetrahydrofuran;hexane at -78; for 1 h;
Stage #2: ethyl 3-furancarboxylate in tetrahydrofuran;hexane at -78; for 2 h;
References:
Xu, Kai;Liu, Hao;Hou, Yilin;Shen, Jiefeng;Liu, Delong;Zhang, Wanbin [Chemical Communications,2019,vol. 55,# 88,p. 13295 - 13298] Location in patent:supporting information