3-[4-(Methoxycarbonyl)phenyl]propanoic acid synthesis

4synthesis methods

Product Name:3-[4-(Methoxycarbonyl)phenyl]propanoic acid
CAS Number:151937-09-6
Molecular formula:C11H12O4
Molecular Weight:208.21

19473-96-2 Synthesis

19473-96-2
22 suppliers
$114.00/1 g

3-[4-(Methoxycarbonyl)phenyl]propanoic acid

151937-09-6
39 suppliers
$14.00/250mg

Yield:151937-09-6 90%

Reaction Conditions:

with hydrogen in methanol at 40; for 5 h;

Steps:

2 Example 2: A method for preparing Compound 2, the process is as follows:
20 g of the compound obtained by the preparation of Example 1, 6.0 g of Raney catalyst, and 500 mL of methanol were added to the reaction flask, and a 1000 mL three-necked flask was used, and hydrogen gas was passed through at 40° (1; heating reaction for 5 hours, and Raney catalyst was removed by filtration. Evaporation of the solvent gave 218.0 g of a white solid compound (yield: 90%).Ethyl acetate = 2:1, Rf = 0.7), GF254 showed only one spot under fluorescence, and Compound 2 was obtained;

References:

Nanjing Yadong Qitian Pharmaceutical Co., Ltd.;Cai Huiming;Lu Jinrong;Zhou Qingfa;Wang Jiahua CN109721604, 2019, A Location in patent:Paragraph 0045; 0046

FullText

(2E)-3-[4-(methoxycarbonyl)phenyl]prop-2-enoic acid

117390-07-5
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inquiry

151937-09-6
39 suppliers
$14.00/250mg

References

40912-11-6 Synthesis

Methyl 3-(4-Methoxycarbonylphenyl)propionate

40912-11-6
37 suppliers
$12.00/250mg

151937-09-6
39 suppliers
$14.00/250mg

References

1571-08-0 Synthesis

1571-08-0
318 suppliers
$10.00/5g

151937-09-6
39 suppliers
$14.00/250mg

References