![](/CAS/20180601/GIF/1080636-43-6.gif)
3-[4-(trifluoromethyl)phenyl]cyclobutan-1-one synthesis
- Product Name:3-[4-(trifluoromethyl)phenyl]cyclobutan-1-one
- CAS Number:1080636-43-6
- Molecular formula:C11H9F3O
- Molecular Weight:214.18
![N,N-Dimethylacetamide](/CAS/GIF/127-19-5.gif)
127-19-5
806 suppliers
$5.00/25g
![4-(TRIFLUOROMETHYL)STYRENE](/CAS/GIF/402-50-6.gif)
402-50-6
134 suppliers
$15.00/500mg
![3-[4-(trifluoromethyl)phenyl]cyclobutan-1-one](/CAS/20180601/GIF/1080636-43-6.gif)
1080636-43-6
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Yield:1080636-43-6 66%
Reaction Conditions:
Stage #1: N,N-dimethyl acetamidewith trifluoromethylsulfonic anhydride in 1,2-dichloro-ethane at 5; for 0.5 h;
Stage #2: 1-trifluoromethyl-4-vinyl-benzene in 1,2-dichloro-ethane; for 18 h;Reflux;
References:
Chernykh, Anton V.;Radchenko, Dmytro S.;Chernykh, Alla V.;Kondratov, Ivan S.;Tolmachova, Nataliya A.;Datsenko, Olexandr P.;Kurkunov, Maxim A.;Zozulya, Sergey X.;Kheylik, Yuri P.;Bartels, Katharina;Daniliuc, Constantin G.;Haufe, Günter [European Journal of Organic Chemistry,2015,vol. 2015,# 29,p. 6466 - 6471] Location in patent:supporting information
![4-(TRIFLUOROMETHYL)STYRENE](/CAS/GIF/402-50-6.gif)
402-50-6
134 suppliers
$15.00/500mg
![3-[4-(trifluoromethyl)phenyl]cyclobutan-1-one](/CAS/20180601/GIF/1080636-43-6.gif)
1080636-43-6
10 suppliers
inquiry