3-ANILINO-3-OXOPROPANOIC ACID synthesis
- Product Name:3-ANILINO-3-OXOPROPANOIC ACID
- CAS Number:15580-32-2
- Molecular formula:C9H9NO3
- Molecular Weight:179.17
76311-94-9
3 suppliers
inquiry
15580-32-2
59 suppliers
$45.00/5mg
Yield:15580-32-2 91.3%
Reaction Conditions:
with lithium hydroxide;water in tetrahydrofuran;methanol at 20; for 3 h;
Steps:
20.b
b) N-Phenyl-malonamic acid Hydrolysis of the N-Phenyl-malonamic acid methyl ester from step a (6.8 g, 35.2 mmol) with lithium hydroxide (8.9 g, 212 mmol) in a mixture of methanol (160 mL), tetrahydrofuran (160 mL) and water (160 mL) at room temperature for 3 h, afforded the title acid (5.76 g, 91.3%). 1H NMR (400 MHz, DMSO-d6) δ: 12.64 (s, 1H), 10.11 (s, 1H), 7.58 (d, 2H), 7.31 (t, 2H), 7.06 (t, 1H), 3.36 (s, 2H).
References:
US2005/107355,2005,A1 Location in patent:Page/Page column 34
2033-24-1
665 suppliers
$6.00/25g
62-53-3
679 suppliers
$10.00/1g
15580-32-2
59 suppliers
$45.00/5mg
1161433-07-3
0 suppliers
inquiry
15580-32-2
59 suppliers
$45.00/5mg
![Ethyl 3-[N-(phenyl)amino]-3-oxopropionate](/CAS/20150408/GIF/53341-66-5.gif)
53341-66-5
18 suppliers
$220.00/250mg
15580-32-2
59 suppliers
$45.00/5mg
62-53-3
679 suppliers
$10.00/1g
15580-32-2
59 suppliers
$45.00/5mg