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3-(Carboxymethyl)-1H-indole-2-carboxylic acid synthesis

10synthesis methods
Methyl 3-(2-methoxy-2-oxoethyl)-1H-indole-2-carboxylate

156362-00-4
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Yield:31529-27-8 90%

Reaction Conditions:

with lithium hydroxide in tetrahydrofuran;

References:

Shou, Xiaohong;Miledi, Ricardo;Chamberlin, A. Richard [Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,# 17,p. 3942 - 3947]