3-(CHLOROMETHYL)-4-METHYLPYRIDINE synthesis

Yield:-

Reaction Conditions:

with thionyl chloride in dichloromethane for 4 h;Ambient temperature;

References:

Bell, Ian M.;Erb, Jill M.;Freidinger, Roger M.;Gallicchio, Steven N.;Guare, James P.;Guidotti, Maribeth T.;Halpin, Rita A.;Hobbs, Doug W.;Homnick, Carl F.;Kuo, Michelle S.;Lis, Edward V.;Mathre, David J.;Michelson, Stuart R.;Pawluczy, Joseph M.;Pettibone, Douglas J.;Reiss, Duane R.;Vickers, Stanley;Williams, Peter D.;Woyden, Carla J. [Journal of Medicinal Chemistry,1998,vol. 41,# 12,p. 2146 - 2163]