3-Hydroxy-2,2,4-triMethyl-pentanoic Acid synthesis
- Product Name:3-Hydroxy-2,2,4-triMethyl-pentanoic Acid
- CAS Number:35763-45-2
- Molecular formula:C8H16O3
- Molecular Weight:160.21
918-79-6
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35763-45-2
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Yield:35763-45-2 98.4%
Reaction Conditions:
with dihydrogen peroxide at 80; for 2 h;Temperature;
Steps:
1.1; 2.1; 3.1
The 2,2,4-trimethyl-3-hydroxypentanal obtained above was added to the reaction kettle, the temperature was raised to 80 ° C, and hydrogen peroxide was added dropwise while reacting. The mass fraction of H2O2 in the hydrogen peroxide was 20%, and the amount of hydrogen peroxide was added. It was 571 grams. After 2 hours of reaction, a gas chromatography test was performed. When the content of 2,2,4-trimethyl-3-hydroxyvaleraldehyde was less than 1%, the dropwise addition of hydrogen peroxide was stopped to obtain the crude product 2,2. 4-trimethyl-3hydroxyvaleric acid, recrystallize the crude 2,2,4-trimethyl-3hydroxyvaleric acid with 120 mL of acetonitrile at 40 ° C,Finally, 540 g of 2,2,4-trimethyl-3 hydroxyvaleric acid was obtained with a purity of 98%.The yield of 2,2,4-trimethyl-3hydroxyvaleric acid was 98.4%
References:
CN110724055,2020,A Location in patent:Paragraph 0045; 0047; 0049; 0054; 0056; 0057; 0063; 0065
144-19-4
245 suppliers
$6.00/25g
35763-45-2
10 suppliers
$185.00/50mg
144-19-4
245 suppliers
$6.00/25g
15904-30-0
2 suppliers
inquiry
35763-45-2
10 suppliers
$185.00/50mg
144-19-4
245 suppliers
$6.00/25g
15904-30-0
2 suppliers
inquiry
918-79-6
4 suppliers
inquiry
35763-45-2
10 suppliers
$185.00/50mg