ChemicalBook CAS DataBase List 2,2,4-Trimethyl-1,3-pentanediol

2,2,4-Trimethyl-1,3-pentanediol synthesis

7synthesis methods

Product Name:2,2,4-Trimethyl-1,3-pentanediol
CAS Number:144-19-4
Molecular formula:C8H18O2
Molecular Weight:146.23

2,2,4-Trimethyl-1,3-pentanediol is made by reacting isobutyryl chloride with ethyl isobutyrate.

933-52-8
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144-19-4
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600-36-2 Synthesis

600-36-2
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15904-30-0
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3010-96-6 Synthesis

3010-96-6
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Yield:-

Reaction Conditions:

with hydrogen in butan-1-ol at 135; under 37503.8 Torr;

Steps:

7-1 Example 7-1
6 mL of the catalyst D (20 to 30 mesh) was put into a fixed bed reactor and tested in a continuous trickle-bed mode. 4 wt % of 2,2,4,4-tetramethyl-1,3-cyclobutanediketone was hydrogenated in the above reactor with hydrogen. The hydrogenation factors are listed below: the solvent was n-butanol (BuOH), the WHSV of the feed was 0.24 hr^-1, the liquid hourly space velocity (LHSV) of the feed was 4 hr^-1, the hydrogenation temperature was 135° C., the hydrogenation pressure was 50 kg/cm², in which the hydrogen and the 2,2,4,4-tetramethyl-1,3-cyclobutanediketone had a molar ratio of 69. The hydrogenation result was analyzed by gas chromatography (GC) as indicated below: the conversion rate of the 2,2,4,4-tetramethyl-1,3-cyclobutanediketone was 99.8%, and the selectivity of the CBDO in the products was 10%, as shown in Table 3.

References:

INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE;CHAN, Shu-Hua;HSU, Hsi-Yen;LEE, Chiou-Hwang;LEE, Ying-Chieh US2017/334815, 2017, A1 Location in patent:Paragraph 0032

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