3-Hydroxyphenylacetic acid synthesis
- Product Name:3-Hydroxyphenylacetic acid
- CAS Number:621-37-4
- Molecular formula:C8H8O3
- Molecular Weight:152.15
1878-69-9
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$27.00/1g
621-37-4
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$6.00/1g
Yield:621-37-4 71%
Reaction Conditions:
with copper(I) oxide;1D-1-O-Methyl-muco-inostol;sodium hydroxide in water at 100; for 6 h;
Steps:
7 Example 7: Preparation of m-hydroxyphenylacetic acid:
In a 100 mL hydrothermal synthesis reactor, sodium hydroxide (3 mmol) and water (5 mL) were added.After stirring and stirring, m-iodophenylacetic acid (0.5 mmol) and cuprous oxide (0.05 mmol) were added.White lignan (0.05 mmol), the reaction was stirred at 100 ° C for 6 hours.After cooling, the pH was adjusted to 2 with dilute hydrochloric acid and extracted with ethyl acetate.The extract is concentrated and subjected to column chromatography to obtain m-hydroxyphenylacetic acid.54.0 mg, yield 71%.
References:
Shenyang Pharmaceutical University;Yunnan Tropical Crop Science Institute;Chen Guoliang;Wu Ying;Bao Xuefei;Li Guohua;Liang Xinjie;Jiang Shikuan;Zhou Qifan;Du Fangyu CN109970542, 2019, A Location in patent:Paragraph 0054-0056
103-82-2
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621-37-4
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102-32-9
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451-13-8
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121-71-1
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621-37-4
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156945-58-3
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621-37-4
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13398-94-2
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621-37-4
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