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ChemicalBook CAS DataBase List 3-Nitrophthalonitrile

3-Nitrophthalonitrile synthesis

5synthesis methods
The synthesis of 3-nitrophthalonitrile started with the nitration in position 3 of phthalimide followed by the formation of 3-nitrophthalamide; then dehydration by the thionyl chloride in N, N-dimethylformamide leads to 3-nitrophthalonitrile.
Synthesis of 3-Nitrophthalonitrile
Synthesis of 3-Nitrophthalonitrile
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: SOCl2
2: aq. NH3
3: POCl3

References:

Oshima, Juro;Yoshihara, Toshitada;Tobita, Seiji [Chemical Physics Letters,2006,vol. 423,# 4-6,p. 306 - 311]

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