ChemicalBook CAS DataBase List 3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER

3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER synthesis

12synthesis methods

Product Name:3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER
CAS Number:325142-82-3
Molecular formula:C13H16BF3O2
Molecular Weight:272.07

401-81-0
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$10.00/10 g

73183-34-3
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$6.00/5g

3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER

325142-82-3
98 suppliers
$27.00/1g

Yield: 81%

Reaction Conditions:

with pyridine;cesium fluoride in dimethyl sulfoxide at 105; for 2 h;Inert atmosphere;Schlenk technique;

Steps:

For Liquid Aryl Iodides; General Procedure B
General procedure: An oven-dried Schlenk tube, containing a Teflon-coated magnetic stir bar was charged with CsF (228 mg, 1.5 mmol, 3 equiv) and bispinacolatodiboron (254 mg, 1 mmol, 2 equiv). Under an argon atmosphere, freshly distilled DMSO (0.4 mL), the appropriate aryl iodide (0.5mmol), and pyridine (0.4 to 1 equiv) were added successively. The reaction mixture was heated to 105 °C and stirred for 2 h under argon.

References:

Pinet, Sandra;Liautard, Virginie;Debiais, Mégane;Pucheault, Mathieu [Synthesis,2017,vol. 49,# 21,p. 4759 - 4768]