8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2S)- synthesis
- Product Name:8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2S)-
- CAS Number:300831-21-4
- Molecular formula:C14H25NO4
- Molecular Weight:271.35
924307-76-6
63 suppliers
$105.00/250mg
24424-99-5
863 suppliers
$13.50/25G
300831-21-4
76 suppliers
$88.00/1g
Yield: 85%
Reaction Conditions:
with triethylamine in tetrahydrofuran;water at 15 - 25; for 5 h;
Steps:
5 Example 5:
1.5 g of the compound of formula G 1.0 eq, TEA 2.2 g 2.5 eq,Di-tert-butyl dicarbonate 2.01 g 1.05 eq, THF/ H2O 7.5mL / 2.5mL, reaction at 15 ~ 25 ° C for 5h, add EA 5mL,2N HCl adjusts pH = 6.5, phase separation, aqueous phase with EA 5mL*3 extraction, drying with anhydrous sodium sulfate, filtration and desolvation,Obtained white solid 2.02g, yield 85%
References:
Zhejiang Jiuzhou Pharmaceutical Technology Co., Ltd.;Ye Wenfa;Sun Hai;Li Min CN108689909, 2018, A Location in patent:Paragraph 0069; 0070
24424-99-5
863 suppliers
$13.50/25G
300831-20-3
3 suppliers
inquiry
300831-21-4
76 suppliers
$88.00/1g
1039171-10-2
2 suppliers
inquiry
300831-21-4
76 suppliers
$88.00/1g
1058705-94-4
21 suppliers
inquiry
300831-21-4
76 suppliers
$88.00/1g
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
0 suppliers
inquiry
300831-21-4
76 suppliers
$88.00/1g