3-(1,1-Dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one synthesis
- Product Name:3-(1,1-Dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
- CAS Number:303776-89-8
- Molecular formula:C21H21N3O4S
- Molecular Weight:411.47
118-48-9
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303776-89-8
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: 58 percent / NaH / N,N-dimethyl-acetamide / 20 h / 20 °C
2.1: NaH / tetrahydrofuran / 1.5 h / Heating
2.2: 26 percent / acetic acid / tetrahydrofuran / 1 h / Heating
References:
Tedesco, Rosanna;Shaw, Antony N.;Bambal, Ramesh;Chai, Deping;Concha, Nestor O.;Darcy, Michael G.;Dhanak, Dashyant;Fitch, Duke M.;Gates, Adam;Gerhardt, Warren G.;Halegoua, Dina L.;Han, Chao;Hofmann, Glenn A.;Johnston, Victor K.;Kaura, Arun C.;Liu, Nannan;Keenan, Richard M.;Lin-Goerke, Juili;Sarisky, Robert T.;Wiggall, Kenneth J.;Zimmerman, Michael N.;Duffy, Kevin J. [Journal of Medicinal Chemistry,2006,vol. 49,# 3,p. 971 - 983]
541-28-6
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303776-89-8
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$139.80/10mg
3306-62-5
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303776-89-8
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![Propanoic acid, 3-[[2-(aminosulfonyl)phenyl]amino]-3-oxo-, ethyl ester](/CAS/20180703/GIF/222420-33-9.gif)
222420-33-9
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303776-89-8
6 suppliers
$139.80/10mg