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34945-66-9

3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-carbonitrile synthesis

6synthesis methods
-

Yield:34945-66-9 0.183 g

Reaction Conditions:

with zinc;1,1'-bis-(diphenylphosphino)ferrocene;tris-(dibenzylideneacetone)dipalladium(0) in N,N-dimethyl acetamide at 150;

References:

Watterson, Scott H.;Chen, Ping;Zhao, Yufen;Gu, Henry H.;Dhar, T. G. Murali;Xiao, Zili;Ballentine, Shelley K.;Shen, Zhongqi;Fleener, Catherine A.;Rouleau, Katherine A.;Obermeier, Mary;Yang, Zheng;McIntyre, Kim W.;Shuster, David J.;Witmer, Mark;Dambach, Donna;Chao, Sam;Mathur, Arvind;Chen, Bang-Chi;Barrish, Joel C.;Robl, Jeffrey A.;Townsend, Robert;Iwanowicz, Edwin J. [Journal of Medicinal Chemistry,2007,vol. 50,# 15,p. 3730 - 3742]