(E)-Ethyl 3-(4-(benzyloxy)-3-Methoxyphenyl)acrylate synthesis
- Product Name:(E)-Ethyl 3-(4-(benzyloxy)-3-Methoxyphenyl)acrylate
- CAS Number:38157-08-3
- Molecular formula:C19H20O4
- Molecular Weight:312.36
2426-87-1
1099-45-2
38157-08-3
GENERAL METHOD: Ethoxycarbonylmethylenetriphenylphosphine (1.55 g, 4.46 mmol) was added to a stirred solution of 4-benzyloxy-3-methoxybenzaldehyde (0.73 g, 3.72 mmol) in benzene (10 mL). The reaction mixture was then refluxed for 4 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and the residue was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether, 1:19) to afford the target product ethyl (E)-3-(4-(benzyloxy)-3-methoxyphenyl)acrylate (0.89 g, 90% yield) as a white solid.
2426-87-1
249 suppliers
$8.00/5g
1099-45-2
371 suppliers
$6.00/5g
38157-08-3
41 suppliers
$26.00/250mg
Yield:38157-08-3 99%
Reaction Conditions:
in dichloromethane at 20; for 6 h;Wittig Olefination;
References:
Lalwani, Komal G.;Sudalai, Arumugam [European Journal of Organic Chemistry,2015,vol. 2015,# 33,p. 7344 - 7351]
867-13-0
480 suppliers
$10.00/1g
2426-87-1
249 suppliers
$8.00/5g
38157-08-3
41 suppliers
$26.00/250mg
4046-02-0
412 suppliers
$5.00/100mg
100-39-0
435 suppliers
$10.00/10g
38157-08-3
41 suppliers
$26.00/250mg
2426-87-1
249 suppliers
$8.00/5g
105-36-2
351 suppliers
$5.00/5G
38157-08-3
41 suppliers
$26.00/250mg
121-33-5
1179 suppliers
$9.00/1g
38157-08-3
41 suppliers
$26.00/250mg