4-(2,2,2-trifluoro-1-hydroxyethyl)phenol synthesis
- Product Name:4-(2,2,2-trifluoro-1-hydroxyethyl)phenol
- CAS Number:246245-20-5
- Molecular formula:C8H7F3O2
- Molecular Weight:192.14
81290-20-2
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$13.00/1g
123-08-0
950 suppliers
$5.00/10g
246245-20-5
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Yield:246245-20-5 94%
Reaction Conditions:
Stage #1: (trifluoromethyl)trimethylsilane;4-hydroxy-benzaldehydewith potassium carbonate in N,N-dimethyl-formamide at 20; for 4 h;
Stage #2: with water in N,N-dimethyl-formamide; for 4 h;Acidic conditions;
References:
Cheng, Huicheng;Pei, Yu;Leng, Faqiang;Li, Jingya;Liang, Apeng;Zou, Dapeng;Wu, Yangjie;Wu, Yusheng [Tetrahedron Letters,2013,vol. 54,# 33,p. 4483 - 4486]
![Benzene, 1-methoxy-4-[2,2,2-trifluoro-1-[(trimethylsilyl)oxy]ethyl]-](/CAS/20210305/GIF/403648-66-8.gif)
403648-66-8
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246245-20-5
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1823-63-8
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$15.00/250mg
246245-20-5
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433-27-2
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$12.00/1g
108-95-2
764 suppliers
$14.00/25g
246245-20-5
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201996-23-8
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![1-Naphthalenesulfonic acid, 5-(dimethylamino)-, 1-[4-(acetyloxy)phenyl]-2,2,2-trifluoroethyl ester](/CAS/20210305/GIF/1279691-46-1.gif)
1279691-46-1
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246245-20-5
16 suppliers
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