4-(2,2,2-TRIFLUOROETHYL)ANILINE synthesis
- Product Name:4-(2,2,2-TRIFLUOROETHYL)ANILINE
- CAS Number:131395-17-0
- Molecular formula:C8H8F3N
- Molecular Weight:175.15
62-53-3
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131395-17-0
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Yield:-
Steps:
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere
2: pyridine / chloroform / 20 °C / Cooling with ice; Inert atmosphere
3: aluminum (III) chloride; sodium tetrahydroborate / tetrahydrofuran / 70 °C / Inert atmosphere
4: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C
References:
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.;Nanjing Gear Pharma&tech Co., Ltd.;WANG, Xiaolong;YANG, Anle;JIANG, Hongjian;ZHOU, Jian;CHEN, Lei;JIANG, Xiaolong;YANG, Ling;XU, Hongjiang;GENG, Xiaohan EP3689860, 2020, A1
3764-36-1
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131395-17-0
51 suppliers
$45.00/10mg
91-73-6
87 suppliers
$20.00/1g
131395-17-0
51 suppliers
$45.00/10mg