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4-(2-fluorophenoxy)benzoic acid synthesis

7synthesis methods
JR-13421, 4-(2-Fluorophenoxy)benzonitrile, 97%

864263-01-4
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4-(2-fluorophenoxy)benzoic acid

913828-84-9
11 suppliers
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Yield:913828-84-9 405 mg

Reaction Conditions:

with sulfuric acid;acetic acid;potassium hydroxide in water;Reflux;

References:

Kormos, Chad M.;Jin, Chunyang;Cueva, Juan Pablo;Runyon, Scott P.;Thomas, James B.;Brieaddy, Lawrence E.;Mascarella, S. Wayne;Navarro, Hernán A.;Gilmour, Brian P.;Carroll, F. Ivy [Journal of Medicinal Chemistry,2013,vol. 56,# 11,p. 4551 - 4567]