4-(3-CHLOROPHENOXY)PIPERIDINE HYDROCHLORIDE synthesis

Yield:-

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane at 20; for 2 h;

References:

Xin, Zhili;Zhao, Hongyu;Serby, Michael D.;Liu, Bo;Liu, Mei;Szczepankiewicz, Bruce G.;Nelson, Lissa T.J.;Smith, Harriet T.;Suhar, Tom S.;Janis, Rich S.;Cao, Ning;Camp, Heidi S.;Collins, Christine A.;Sham, Hing L.;Surowy, Teresa K.;Liu, Gang [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 15,p. 4298 - 4302] Location in patent:supporting information; scheme or table