4-(3,4-DICHLOROPHENOXY)PIPERIDINE synthesis
- Product Name:4-(3,4-DICHLOROPHENOXY)PIPERIDINE
- CAS Number:245057-73-2
- Molecular formula:C11H13Cl2NO
- Molecular Weight:246.13
260441-48-3
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245057-73-2
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Yield:245057-73-2 87%
Reaction Conditions:
with hydrogenchloride in ethyl acetate at 25; for 2 h;
Steps:
33.2 Step 2: 4-(3,4-dichlorophenoxy)piperidine.
To a solution of tert-butyl 4-(3,4-dichlorophenoxy)piperidine-1-carboxylate (1.3 g, 3.75 mmol) in EtOAc (10 ml_) was added HCI/EtOAc (4 M, 10 ml_). The mixture was stirred at 25 °C for 2h, filtered and the solids were dried over in vacuo to afford 4-(3,4-dichlorophenoxy)piperidine (0.8 g, 3.25 mmol, 87%) as a white solid.
References:
WO2021/247916,2021,A1 Location in patent:Page/Page column 82; 83
109384-19-2
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245057-73-2
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$163.16/1g
95-77-2
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245057-73-2
30 suppliers
$163.16/1g