4-BROMO-3-TRIFLUOROMETHYL-BENZALDEHYDE synthesis
- Product Name:4-BROMO-3-TRIFLUOROMETHYL-BENZALDEHYDE
- CAS Number:34328-47-7
- Molecular formula:C8H4BrF3O
- Molecular Weight:253.02
957207-09-9
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$64.00/100mg
34328-47-7
113 suppliers
$7.00/100mg
Yield: 82%
Reaction Conditions:
with manganese(IV) oxide in dichloromethane for 12 h;
Steps:
12 Example 12
Example 12
Preparation of 4-bromo-3-(trifluoromethyl)benzaldehyde (C70)
To a solution of (4-bromo-3-(trifluoromethyl)phenyl)methanol (C72) (12.0 g, 47.1 mmol) in dichloromethane (100 mL) was added manganese dioxide (25.6 g, 294 mmol).
After stirring for 12 hours, the mixture was filtered through Celite and the filtrate was concentrated in vacuo to afford the title compound as a pale yellow solid (10.0 g, 82%): 1H NMR (300 MHz, CDCl3) δ 10.05 (s, 1H), 8.19 (s, 1H), 7.94-7.88 (m, 2H); IR (thin film) 1704, 1123 cm-1; EIMS m/z 219 ([M]+).
References:
Dow AgroSciences LLC;LePlae, JR., Paul R.;Barton, Thomas;Gao, Xin;Hunter, James E.;Lo, William C.;Boruwa, Joshodeep;Tangirala, Raghuram;Watson, Gerald B.;Herbert, John;Demeter, David A.;Joshi, Hemant US2018/279612, 2018, A1 Location in patent:Paragraph 0382-0383
393-36-2
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$6.00/1g
34328-47-7
113 suppliers
$7.00/100mg
161622-14-6
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$10.00/1g
34328-47-7
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75-17-2
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$35.00/25mL
393-36-2
313 suppliers
$6.00/1g
34328-47-7
113 suppliers
$7.00/100mg