4'-BROMOBIPHENYL-4-SULFONYL CHLORIDE synthesis
- Product Name:4'-BROMOBIPHENYL-4-SULFONYL CHLORIDE
- CAS Number:13610-11-2
- Molecular formula:C12H8BrClO2S
- Molecular Weight:331.61
78079-08-0
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13610-11-2
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Yield:13610-11-2 100%
Reaction Conditions:
with thionyl chloride at 80; for 4 h;
Steps:
4.2 2.
Preparation of 4-(4-bromophenyl)benzenesulfonyl chloride
4-(4-bromophenyl)benzenesulfonic acid (10.5 g, 33.5 mmol) was dissolved in thionyl chloride (60.0 mL).
The reaction system was heated to 80°C and then reacted for 4h.
The reaction solution was added dropwise in icy water (300 mL), and extracted with ethyl acetate (100mL*2).
The organic layer was dried with anhydrous sodium sulfate and condensed to obtain white solid 4-(4-bromophenyl)benzenesulfonyl chloride (11.5 g, 34.7 mmol, 100% yield).
References:
EP3398598,2018,A1 Location in patent:Paragraph 0098; 0099
92-66-0
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13610-11-2
22 suppliers
$251.00/100mg