
4-(CHLOROMETHYL)-2-(2-THIENYL)-1,3-THIAZOLE synthesis
- Product Name:4-(CHLOROMETHYL)-2-(2-THIENYL)-1,3-THIAZOLE
- CAS Number:54679-16-2
- Molecular formula:C8H6ClNS2
- Molecular Weight:215.72
Yield:54679-16-2 65%
Reaction Conditions:
with thionyl chloride
Steps:
R.76 Reference Example 76
Reference Example 76 In substantially the same manner as in Reference Example 73, 2-(2-thienyl)-4-thiazolylmethanol was allowed to react with thionylchloride to give 4-chloromethyl-2-(2-thienyl)thiazole. The yield was 65%. Recrystallization from ethyl acetate-hexane gave colorless needles, mp 54-55° C.
References:
US6211215,2001,B1

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54679-16-2
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