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ChemicalBook CAS DataBase List 4-Methylbenzyl alcohol

4-Methylbenzyl alcohol synthesis

12synthesis methods
p-Tolyl alcohol is commercially prepared by reducing p-tolyl aldehyde. It is used mainly in fragrances, and the major route of exposure is likely to be dermal contact.
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Yield:589-18-4 100%

Reaction Conditions:

with sodium tetrahydroborate in methanol at 20; for 1 h;

Steps:

Step-I (Preparation of benzyl alcohols)
General procedure: benzaldehyde derivatives (1 mmol) in methanol (15 mL), sodium borohydride (2 mmol) and stirred at room temperature for 1 h. Usual work-up, quantitative yield.

References:

Parihar, Swati;Kumar, Amit;Chaturvedi, Amit K.;Sachan, Naresh Kumar;Luqman, Suaib;Changkija, Bendangla;Manohar, Murli;Prakash, Om;Chanda;Khan, Feroz;Chanotiya;Shanker, Karuna;Dwivedi, Anila;Konwar, Rituraj;Negi, Arvind S. [Journal of Steroid Biochemistry and Molecular Biology,2013,vol. 137,p. 332 - 344]

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