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ChemicalBook CAS DataBase List 4-N-NONYLBENZOYL CHLORIDE

4-N-NONYLBENZOYL CHLORIDE synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran
3: lithium hydroxide / tetrahydrofuran; water / 3 h / Reflux
4: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 0 °C / Inert atmosphere

References:

Stephens, Matthew D.;Yodsanit, Nisakorn;Melander, Christian [MedChemComm,2016,vol. 7,# 10,p. 1952 - 1956]

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