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4-(thiophen-3-yl)-Morpholine synthesis

4synthesis methods
-

Yield:1006-76-4 99%

Reaction Conditions:

with (1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene)Pd(cinnamyl, 3-phenylallyl)Cl;sodium t-butanolate in neat (no solvent) at 110; for 12 h;Inert atmosphere;Green chemistry;Buchwald-Hartwig Coupling;

References:

Topchiy, Maxim A.;Dzhevakov, Pavel B.;Rubina, Margarita S.;Morozov, Oleg S.;Asachenko, Andrey F.;Nechaev, Mikhail S. [European Journal of Organic Chemistry,2016,vol. 2016,# 10,p. 1908 - 1914] Location in patent:supporting information