
4-(thiophen-3-yl)-Morpholine synthesis
4synthesis methods
- Product Name:4-(thiophen-3-yl)-Morpholine
- CAS Number:1006-76-4
- Molecular formula:C8H11NOS
- Molecular Weight:169.24
Yield:1006-76-4 99%
Reaction Conditions:
with (1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene)Pd(cinnamyl, 3-phenylallyl)Cl;sodium t-butanolate in neat (no solvent) at 110; for 12 h;Inert atmosphere;Green chemistry;Buchwald-Hartwig Coupling;
References:
Topchiy, Maxim A.;Dzhevakov, Pavel B.;Rubina, Margarita S.;Morozov, Oleg S.;Asachenko, Andrey F.;Nechaev, Mikhail S. [European Journal of Organic Chemistry,2016,vol. 2016,# 10,p. 1908 - 1914] Location in patent:supporting information