4'-TRIFLUOROMETHOXY-BIPHENYL-4-YLAMINE synthesis
- Product Name:4'-TRIFLUOROMETHOXY-BIPHENYL-4-YLAMINE
- CAS Number:728919-14-0
- Molecular formula:C13H10F3NO
- Molecular Weight:253.22
![1-Nitro-4-[4-(trifluoroMethoxy)phenyl]benzene](/CAS/GIF/1019996-86-1.gif)
1019996-86-1
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$200.00/500mg
728919-14-0
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$280.00/1g
Yield:728919-14-0 100%
Reaction Conditions:
with hydrogenchloride;iron in ethanol;water at 110; for 4 h;
Steps:
7.2 Step 2: Preparation of 4'-(trifluoromethoxy)-1,1'-biphenyl-4-amine (7b)
4-nitro-4'-(trifluoromethoxy)-1,1'-biphenyl (7a) 2.2 g (7.7 mmol) in ethanol 40 ml,10 ml of distilled waterAnd add 4.33g (77mmol) of iron, 3 drops of concentrated hydrochloric acid were added and reacted at 110° C. for 4 hours. When the reaction was completed, the residue was filtered through celite and concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (eluent, ethyl acetate/normal-hexane = 1/4) to obtain the target compound 7b as a brown solid (2g, Quantitative).
References:
KR101564425,2015,B1 Location in patent:Paragraph 0145; 0146; 0150-0152
106-40-1
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139301-27-2
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728919-14-0
20 suppliers
$280.00/1g
540-37-4
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139301-27-2
393 suppliers
$14.00/5G
728919-14-0
20 suppliers
$280.00/1g
139301-27-2
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$14.00/5G
728919-14-0
20 suppliers
$280.00/1g
586-78-7
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$14.00/5g
728919-14-0
20 suppliers
$280.00/1g