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4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone synthesis

5synthesis methods
-

Yield:43076-30-8 79%

Reaction Conditions:

with [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2;triethylamine in acetone at 150;Flow reactor;

References:

Labes, Ricardo;Battilocchio, Claudio;Mateos, Carlos;Cumming, Graham R.;De Frutos, Oscar;Rincón, Juan A.;Binder, Kellie;Ley, Steven V. [Organic Process Research and Development,2017,vol. 21,# 9,p. 1419 - 1422] Location in patent:supporting information