1-(4-FLUOROBENZYL)-2-(TRIFLUOROMETHYL)-1H-1,3-BENZIMIDAZOLE synthesis
1synthesis methods
- Product Name:1-(4-FLUOROBENZYL)-2-(TRIFLUOROMETHYL)-1H-1,3-BENZIMIDAZOLE
- CAS Number:478030-39-6
- Molecular formula:C15H10F4N2
- Molecular Weight:294.25
Yield:478030-39-6 93%
Reaction Conditions:
with copper(l) iodide;N,N,N,N,-tetramethylethylenediamine;caesium carbonate in toluene at 20 - 110; for 8.5 h;Inert atmosphere;
References:
Chen, Mu-Wang;Zhang, Xing-Guo;Zhong, Ping;Hu, Mao-Lin [Synthesis,2009,# 9,art. no. F25208SS,p. 1431 - 1436] Location in patent:experimental part