![](/CAS/GIF/494210-61-6.gif)
2H-Thiopyran-4-carboxaldehyde, tetrahydro-, 1,1-dioxide synthesis
- Product Name:2H-Thiopyran-4-carboxaldehyde, tetrahydro-, 1,1-dioxide
- CAS Number:494210-61-6
- Molecular formula:C6H10O3S
- Molecular Weight:162.21
![1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid](/CAS/GIF/64096-87-3.gif)
64096-87-3
113 suppliers
$24.73/250mgs:
![2H-Thiopyran-4-carboxaldehyde, tetrahydro-, 1,1-dioxide](/CAS/GIF/494210-61-6.gif)
494210-61-6
35 suppliers
$285.00/100mg
Yield: 73%
Reaction Conditions:
Stage #1:1,1-dioxo-hexahydro-1λ6-thiopyran-4-carboxylic acid with 2,6-dimethylpyridine;nickel(II) bromide trihydrate;4,4'-di-tert-butyl-2,2'-bipyridine;zinc;dimethyl dicarbonate in ethyl acetate for 0.25 h;Inert atmosphere;Green chemistry;
Stage #2: with diphenylsilane in ethyl acetate at 60; for 16 h;Inert atmosphere;Green chemistry;
References:
Iosub, Andrei V.;Moravčík, Štefan;Wallentin, Carl-Johan;Bergman, Joakim [Organic Letters,2019,vol. 21,# 19,p. 7804 - 7808] Location in patent:supporting information
![Tetrahydrothiopyran-4-carbaldehyde](/CAS/GIF/50675-19-9.gif)
50675-19-9
69 suppliers
$45.00/50mg
![2H-Thiopyran-4-carboxaldehyde, tetrahydro-, 1,1-dioxide](/CAS/GIF/494210-61-6.gif)
494210-61-6
35 suppliers
$285.00/100mg
![2H-Thiopyran-4-Methanol, tetrahydro-, 1,1-dioxide](/CAS/GIF/473254-28-3.gif)
473254-28-3
27 suppliers
$45.00/10mg
![2H-Thiopyran-4-carboxaldehyde, tetrahydro-, 1,1-dioxide](/CAS/GIF/494210-61-6.gif)
494210-61-6
35 suppliers
$285.00/100mg