5-Azoniaspiro[4.4]nonane chloride synthesis
- Product Name:5-Azoniaspiro[4.4]nonane chloride
- CAS Number:98997-63-8
- Molecular formula:C8H16ClN
- Molecular Weight:161.6723
123-75-1
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$10.00/5g
110-56-5
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98997-63-8
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$45.00/10mg
Yield:98997-63-8 88%
Reaction Conditions:
with potassium hydroxide in water at 20 - 100;
Steps:
Synthesis of 5-azoniaspiro|"4.4"|nonane chloride:
0.02 mol of KOH in 15 mL water were kept under stirring at 100 °C for 10 min, then 0.02 mol of pyrrolidine were slowly added to the mixture at the same temperature and, after 5 min, 0.02 mol of 1,4-dichlorobutane were slowly added. The solution was kept at 100 °C for 18 h, then 1 night at room temperature. The solvent was eliminated under reduced pressure, obtaining a solid, which was dissolved in CHCI3 and filtrated. The chloroform phase was concentrated under vacuum, obtaining 2.84 g of pure 5-azoniaspiro[4.4]nonane chloride (88%).
References:
WO2017/137343,2017,A1 Location in patent:Page/Page column 8
110-56-5
305 suppliers
$15.00/25mL
98997-63-8
27 suppliers
$45.00/10mg
![5-Azoniaspiro[4.4]nonane,bromide (1:1)](/CAS/20180808/GIF/16450-38-7.gif)
16450-38-7
33 suppliers
$45.00/10mg
98997-63-8
27 suppliers
$45.00/10mg