5-Chloro-4-methyl-thiophene-2-carboxylic acid synthesis

1synthesis methods

Yield:74598-03-1 89%

Reaction Conditions:

with n-butyllithium in diethyl ether;1.) reflux, 2 h, 2.) - 70 deg C;

References:

Clarke, Kenneth;Fox, William Richard;Scrowston, Richard M. [Journal of the Chemical Society. Perkin transactions I,1980,p. 1029 - 1037]

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