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5-Chloro-N-(2-Methylbenzyl)pyrazine-2-carboxaMide synthesis

2synthesis methods
34604-60-9 Synthesis
5-Hydroxypyrazine-2-carboxylic acid

34604-60-9
209 suppliers
$15.00/1g

5-Chloro-N-(2-Methylbenzyl)pyrazine-2-carboxaMide

1438853-95-2
4 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: thionyl chloride; N,N-dimethyl-formamide / toluene
2: triethylamine / acetone

References:

Servusová, Barbora;Vobicková, Jana;Paterová, Pavla;Kubí?ek, Vladimír;Kune?, Ji?í;Dole?al, Martin;Zitko, Jan [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 12,p. 3589 - 3591]