5-IODO-2-PYRROLIDIN-1YLPYRIDINE synthesis
- Product Name:5-IODO-2-PYRROLIDIN-1YLPYRIDINE
- CAS Number:494771-62-9
- Molecular formula:C9H11IN2
- Molecular Weight:274.1
123-75-1
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69045-79-0
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494771-62-9
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Yield:-
Reaction Conditions:
with potassium carbonate in DMF (N,N-dimethyl-formamide) at 130; for 16 h;
Steps:
20.A Step A
[0204] To a solution of chloroiodopyridine (1.2 g), pyrrolidine (1.2 ml) and potassium carbonate (2.0 g) in DMF was heated 130° C. for 16 h. The mixture was cooled to RT and poured into ice/water to give crude solid material. The title compound was crystallized from hexanes/ethyl acetate (0.73 g). [0205] 1H NMR (CDCl3): 8.30 (1H, d); 7.62 (1H, dd); 6.23 (1H, d); 3.43 (4H, m); 2.03 (4H, m).
References:
US2004/97575,2004,A1 Location in patent:Page 18
210963-93-2
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494771-62-9
24 suppliers
$46.10/250mg