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ChemicalBook CAS DataBase List 5-tert-butoxyquinazoline-2,4-diaMine

5-tert-butoxyquinazoline-2,4-diaMine synthesis

2synthesis methods
1897-52-5 Synthesis
2,6-Difluorobenzonitrile

1897-52-5
513 suppliers
$7.00/10g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydride / tetrahydrofuran; mineral oil / 6 h / 0 - 20 °C / Inert atmosphere
2: N,N-dimethyl acetamide / 8 h / 140 °C

References:

Chao, Bo;Tong, Xian-Kun;Tang, Wei;Li, De-Wen;He, Pei-Lan;Garcia, Jean-Michel;Zeng, Li-Min;Gao, An-Hui;Yang, Li;Li, Jia;Nan, Fa-Jun;Jacobs, Michael;Altmeyer, Ralf;Zuo, Jian-Ping;Hu, You-Hong [Journal of Medicinal Chemistry,2012,vol. 55,# 7,p. 3135 - 3143]