5-Thiazolecarboxaldehyde, 2-(2-fluorophenyl)- synthesis

2synthesis methods

Product Name:5-Thiazolecarboxaldehyde, 2-(2-fluorophenyl)-
CAS Number:914347-94-7
Molecular formula:C10H6FNOS
Molecular Weight:207.22

1993-03-9 Synthesis

1993-03-9
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5-Thiazolecarboxaldehyde, 2-(2-fluorophenyl)-

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Yield:-

Steps:

Multi-step reaction with 3 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / 1,4-dioxane; water / 12 h / 110 °C / Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C
3: manganese(IV) oxide / dichloromethane / 12 h / 20 °C

References:

WO2021/62318,2021,A1

5-Thiazolecarboxylic acid, 2-(2-fluorophenyl)-, ethyl ester

400715-48-2
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914347-94-7
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References

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