trans-2-(4-methoxyphenyl)cyclopropane-1-carboxylic acid synthesis
- Product Name:trans-2-(4-methoxyphenyl)cyclopropane-1-carboxylic acid
- CAS Number:5087-21-8
- Molecular formula:C11H12O3
- Molecular Weight:192.21
637-69-4
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: copper(II) bis(trifluoromethanesulfonate); 2,2'-isopropylidenebis[(4S)-4-tert-butyl-2-oxazoline] / chloroform / 5 h / Inert atmosphere
2: triethylsilane; trifluoroacetic acid / dichloromethane / 1.5 h
References:
Benelkebir, Hanae;Hodgkinson, Christopher;Duriez, Patrick J.;Hayden, Annette L.;Bulleid, Rosemary A.;Crabb, Simon J.;Packham, Graham;Ganesan [Bioorganic and Medicinal Chemistry,2011,vol. 19,# 12,p. 3709 - 3716]
943-89-5
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3901-07-3
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948551-64-2
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